I've had a .300 W Contender barrel since they first came out. DO NOT consider subsonic loads for deer! These were designed for sniper use on enemy helmets, not for lung shots on deer; the long, heavy bullets will not expand and they cannot be depended upon to tumble with adequate penetration.
The .300 does very well with 125-grain Ballistic Tips, and their velocity does not need to be maximum for up to 100 yard shots. I used these bullets in a .30 Carbine barrel loaded to 1850 fps ( way too hot, do not try it!) and they killed Kodiak Island deer very well. The .300 can get up to 200 fps more out of the same bullet and has a great reputation. Some use the 150 BTips, particularly in longer barrels. The .300 isn't quite as potent as the .30 Herrett, but it is a fine choice for the recoil-shy.