I recently had a much rarer and better rifle than a Pre-64 Mod. 70 rechambered from 7x57 to .280. this is a genuine, original Brno Mod. 21-H "roundbolt" and is one of only a few hundred ever made; the total number of Brno 21-22 series rifles made is somewhat over 40,000. This rifle had very good metal, but, hard use had battered the stock, so, I decided to rebuild the stock and, due to a very long throat, re-chamber the rifle.
My loads push the Nosler Part. Gold Moly-Free 160 gr. at 2800+ fps. and the groups are usually about .6, with a 3-9 scope. The whold rig is very light and trim, the balance is superb. So, I would say, do it, the .280 is just a superb round when properly handloaded and the rifle you have is not really worth keeping as a collector's piece. For those who may think that I am slagging the sacred "old" Mod. 70, I have now owned 33 of them and currently own 10 plus 2 factory H&H actions. They were and are a fine rifle, but a Brno 21-22 or ZG-47 is better, IMO.