The number one issue is put the bullet where the light is if you want to knock the lights out! So stay with your accurate load. You are working at a velocity where cast of almost any alloy will hold together well, and if hardness is over 20 bhn, will not expand or breakup at all unless a heavy bone is hit. So your stout load will perform on any game you want to hunt on this continent.
Of interest to other shooters. Cast bullets at speeds over 2600 fps can blow to powder on impact in extreemly cold weather. Say 0 deg. F and below. My book was written while I lived in Arizona, where I never shot large game at temperatures below 10 deg. F, so the high velocity performance I talk about is limited to temperatures above 10 deg F. Up here in North Idaho, there are times when 10 degrees seems like spring has arrived, and I've learned to hold a 2400 fps velocity ceiling with lead, for big game hunting loads.
Ironically, high velocities are easy to obtain in cool temperatures, say 60 deg F and below, when using LBT bullet designs and lubricant. The 7 and 30 magnums can be run at max throttle (3300-3400 fps) with good hunting accuracy. But don't shoot anything larger than maybe 75 pounds with such loads. The cold lead which makes heavy loads like this possible, is too brittle to withstand the high speed impact is antimony content is over 1%. In other words, wheel weight alloy with 2% tin added, then diluted with half lead. Bullets oven heat treated to get the hardness up to stand high chamber pressures. If you want to experiment with the highest possible velocities for big game, that is your alloy and method. Test the bullets ability to hold together on impact by shooting into water filled plastic jugs at close range in the coldest weather you think you many encounter when hunting. I put a piece of 2 by framing lumber behind one one gallon jug. If the bullet makes it through the 1 1/2 inch of fir plank after smacking the water, it will work fine on game up to at least elk. If you get only pieces hitting the plank, lower the velocity. Don't step outside with gun and ammo warmer than ambient to do this test. Leave them in the cold till they are down to ambient temperature. Stay inside and sip coffee if you like while the gun is chilling. Your body temperature won't effect the bullets performance!!