Sorry, no input on the grip frame but I will offer this. Any of my single six's are capable of consistantly taking small game out to 50-60' or so. ( 30' for headshots) with iron sights. Admittedly though, my shortest SS is 5.5".
FWIW, I'd offer two other thoughts.
1) With all those mods, your talking about dumping some significant $ into a Ruger SS if I'm not mistaking. I would offer that for around the same $ you could get into a nice S&W mod 17/617 in 4" or 6" barrel and have (slightly to significantly)better accuracy and an all steel DA revolver.
2) a Ruger MK II target pistol ( 5.5 or 6 7/8")will be about 1/2 again as accurate ( in my experience) as the single six and has a much MUCH better sight radious. OF course, if you didn't like the 6.5" barrel on your old single six, I'm not sure you'd feel any different about a long barreled MK II.