I have a 375 win big bore and have killed many a deer with it.the lyman mold (gc) drops about 270 grs from my alloy.I have also tried my 38/55 bullet 240 gr plain base sized .376 that also shoots good.I have not used this bullet on game yet.
with the 375 win loads(270 gr gc) the longest I had to track a deer was about 20 feet :grin: I have used IMR 4227 and RL7 for best results.keep the load to about 1500 fps for best accuracy.
txpete