In my Mark V Sporter = 220's. I do all my deer inside 125yds. The rounds are far under the weatherby claim of 1.5" at 100yds.
For deer, I have my highest percentage of on the spot kills with 3006 220's. (also big fan of .300 Sav. 180's). And very minimal meat loss, should I miss a little forward and catch a shoulder. I'm all about meat, and from my perspective that equates to big and slow, and consistent pass through...