Ok, I'll go first...
If I had one rifle for hunting browns and grizzly it would be a? 375 H&H. Seems like a good compromise between knock 'em down flat and reach out and touch 'em. As long as we're dreaming, I've also seen some beautiful double rifles; 475 NE, for example. I'm thinking that in the alders, I'd rather just have...someone else right in front of me squeelin' like a stuck pig :wink: .
If I had one rifle for everything else except hunting browns and grizzly it would be a? 300 Win Mag Flat trajectory and plenty of punch once it got there.
If I had one rifle for hunting goats and sheep it would be a? 300 Win Mag.
Frankly, if I'm hunting something I truly care about, I'm all business. I'm looking for the most effective rifle available. If it's more for 'fun' I like my Freedom Arms 454, my longbow, or dad's old Marlin 35 Rem :-) .