I don't think heavy barrels are anymore intrinsically accurate. They are favored by varmint shooters who shoot a lot of bullets in a short period or time. For a deer rifle I would consider where and how I hunt. Are you going to be in a stand all day or do you move around? How does the barrel configuration handle for you? Lastly, what appeals to you aesthetically? As far as caliber........from the options you have selected........the deer isn't going to care. If I was allowed only one caliber it would be the 30-06.