It's my opinion, and it is just an opinion, that you can use loads identified in most reloading manuals as being .45 Colt loads for Contenders, Rugers, and the Colt Anaconda. The Anaconda chambers near the bolt notch are probably thinner than the Contender barrel walls. These loads are typically in the 25,000 CUP range. I think what is going to limit you is the recoil of this light barrel. I find it really unpleasant. Anyhow, you can use loads somewhere between standard loads and these hotter loads to very good effect on deer out to around 75 yards. The 45 is a BIG hunk of lead; it doesn't have to be going too fast to do the job.
RonF