I load Win.-296 in all of my mag. handgun ammo. Everything from .357 to .500. It seem to give you the most velosity for the least presure. I have alway had real good luck with it as far as accuracy is conserned also. H-110 is about the same thing, but I can get the 296 cheaper most of the time. I but it in 8 lb. jugs and usually burn one in a year or less, so I have used quite a bit of it.