I have been useing Win.-296 in all of my mag. handgun loads for years. It give you the most velosity for the lowest presure and I`ve always gotten good accuracy with it. I load it in everything from .357`s to the .500 S&W. H-110 is about the same thing but I can find 296 cheaper, and don`y worry if you have alittle dust in the barrel after fireing it. It will wipe out with 1 patch and does not affect accuracy.