There is a wealth of info in the - World of Black Powder Cartridge Rifles, Loading, Shooting and Reloading section of this Forum, also the MSN BPCR Forum and the Shiloh Forum. Searches within Forums should help as the .45-110 pops up from time to time, with many guys shooting it. I have fired rifles in .45-110, but have not loaded for it. Dozer is right - 1f powder does kick less. good luck....