C2ND -
First, let me say WELCOME!
A 1" wall thickness is "right-much strong" in DOM. Engineering can be done in at least two ways. One, run the numbers based on proper theory, education and experience (qualifications as an engineer in the area). OR, since most of us don't fit into that category, look at what others have proven by experience over a long time and build it stronger.
If I'm not mistaken, the N-SSA requires that cannon used in their competitions must be steel tube (seamless) lined and the lining be 3/8" wall thickness (check it out in their regulations, don't trust my memory). That should tell you something right off the bat on the relative strength of 1" wall thickness DOM tubing.
DD has some references (as the More Complete Cannoneer - if I remember the title correctly) that give some good rules of thumb as to powder charge, size of powder chamber, windage and such. Those are good starting places.
With DOM, you have the issue of how to seal one end - threaded with crush fit shoulder and then welded further back (not welded in the area where the porosity of the weld would come in contact with the products fo combustion.
This is a start on the answer to your question, others will undoubtedly pitch in.
Good luck, keep us informed and post some pictures!