third_rail,
Welcome to the board. Unheat treated 4140 has a minimum yield strength of 60,000 psi so you should be fine with the load you propose. If the steel has been heat treated, that figure goes way up. Check your steel supplier to find out if it's been heat treated. Stronger is better.
If you can get some 1144 Stressproof, it has a yield strength of 100,000 psi without having to be heat treated.
I've fired 150gr of 2Fg in a normal sized cap & ball rifle and the recoil is less than my M1. Granted, your projectile will be more massive, but 150gr is a fairly light load for what your proposing so I don't think recoil will be much of a factor.
The NPS has a flintlock wall gun at the Castillo de San Marcos in St. Augustine, FL that is absolutely MASSIVE. Next time I'm there, I'll get some pictures and post them.