I've got to chime in on this one.......I have rifles from .17 cal up......... I bought a .45/70 last year for a couple of different reasons. First, of the many deer I've killed, 90 yards was the farthest, and I'd wager that most deer are killed at 60 yards or less.......Muzzleloaders account for a lot of game at that range as well, and have been killing game for a long time. With the encroachment of the city into the country side, I wanted a rifle that under normal conditions wouldn't leave the county, but would drop like a rock after a few hundred yards. Second, the big bores are useful on large game hitting hard like no small bore. Third, I like the nostalga of hunting with a 120 or so year old cartridge. The big bores are just plain fun to shoot, and the 45.70 has become one of my favorites.
As for the 444, I'd love to have one, as it's a fine short to medium range round that makes big holes...........and would be fine for anything in the lower 48 and would probably be fine for all but the largest bears up in the frozen north.........It would probably be fine for them as well with proper bullet placement. Each unto his own, but don't knock it until you've tried it!