It is a balancing act. You have to decide what you want to "make work..."
Last century, with smokeless powder, high velocity became possible. Higher with lighter bullets.
.220 Swift was the "queen bee" for a long time. 48 grain bullet. If it got inside the rib cage and blew up there, it would kill about anything. IF. The bullet might well blow up on a rib or a clod of dirt clinging to the coat... Now we have the .17 Rem exceeding it.
At the other extreme, 6.5 Swede had a long, honored rep for putting a heavy, slow moving bullet thru the guts of large beasts and causing enough disruption, they died....
Last couple decades have been a "meeting of sorts." The first .223 military was twisted 1 in 12 I think, so the 55 grain boat tail bullet would tumble and cause more damage. Before this factory centerfire .224s had been 1 in 14. Wasn't enough. They went to a much longer 62 grain bullet with steel insert and it needed a 1 in 8 twist or 1 in 9 or 1 in 7...
Faster twists wear faster... If you go with a .22-6mm Imp and fast twist and heavy bullets, you can make it shoot, but you will not have the barrel life of a .223. .284 holds about the powder of a .30/'06 case so any of the '06 family records applies. .270 WCF (.27/'06), .25/'06, etc. 6.5/'06 is quite well thought of, just not common when the .270 was so close and factory. .284 case has a great rep for accuracy and one less round in magazine
Your call. LUCK.