Buckeyeppc,
I just found this tread. If you haven't taken any action yet, consider rechambering to 225 Winchester. This is a standard chambering, not a wildcat, so reamers should be easy to find. Also a rimmed case, which Handis seem to prefer. Winchester brass is available from Midway and this caliber performs very well. It operates at about 50,000 psi, and performs just under the 22-250. I once had a Savage bolt in this caliber and it killed a lot of crows sitting in our corn fields. (Of course, this was before crows were protected in Washington state.)
Wally