Just be aware the 30-06 can do it, but it is classified as the bare minimum. I personally carry a 30-06 in the winter time. Come spring I carry a .338 Win. Mag. or one of the .35s. All we have here is Grizzlies (same bear just don't get as big as the Coastal bears). When I go to the coast I carry the .338 only. I have a very interesting video of Jim Schokley, the Canadian Guide that has taken everything with a muzzleloader. He went after a Coastal Brown with an Encore .50 cal, he will never do that again, and advises no one else try it. Jim shot the bear twice I believe, but it took several shots from the guides .375H&H to finally stop the beast. Jim feels that a muzzleloader is just not adequate for the job. I feel the same about a 30-06, or anything smaller than .338.