In the 1950's before there were so many medium bore magnum cartridges, the Barnes 250 loaded in 30-06 were popular for Alaskan Brown bear. I read about them as a kid but never found the bullets until the 1980's. Have one box still but I've only loaded them in my 300 win mag. for range experiments. I think the partitions, fail safes and X Bullets in the 200 gr range may be a better choice these days.