Depends on a combination of how much flare you put on, and how tight your chamber is. On my Browning 40/65, I like to make the mouth straight. No real crimp, but just enough to straighten out the flare.
At first, I just left the flare there. Some people wrote that the flare would help to center the cartridge in the chamber. But one time, in the middle of a match, my cartridge would not go all the way into the chamber! The flare, along with the fouling, made it a really tight fit. So from then on, I started using the crimp die just enough to take the flare out.
There was no difference in accuracy.
On my Shiloh 40/70 Straight, I leave the flare alone. I have only had this rifle for a few months, but so far this seems to work OK.
BTW - if you need to crimp, and want to do it as a separate operation, I highly recommend Lyman's taper crimp dies for BPCR. They make them in 3 sizes: 40, 45 Short, and 45 Long. The 45 Short is for everything up to and including 45/100, and the 45 Long is for 45/110 and 45/120.