Lawful Larry, for the last few years I have been using APP under a 200 or 250 grn hard cast slug for deer and have has good performance from this load. I used to load realy hot 45lc loads and the deer I have shot with the APP loads couldn't tell the diference between my APP oads and the realy hot loads I used to use. I have hunted from the same blind for close to 10 years now, and the shots range from about 10ft to, at the most, 50yds. I am a firm believer in using enough gun for the job, but see no reason to use more than I need to humainly kill the game I'm hunting. And I got tired of beating up my hands and my pistols with the realy hot loads.
However, earlier today, I did shoot a gopher in the back yard and I think I used more gun than I needed for that. I shot it with my Winchester model 86, made in 1891, in 45-70 caliber, loaded with 65grns of APP under a hardcast 405grn RNFP slug.
It was a one shot kill.
Greeenriver(Shoot what you enjoy, shooting is suposed to be fun.)