Robert, as Mac said, it will probably work, just depends on the position of the scope and the size of the ocular bell/power ring. I use medium sig zees 99% of the time, but some scopes require the high sig zees. I can usually get away with placing the power ring just behind the hammer so it gives me just a little clearance in just the right spot, but that is a configuration that fits me well and may not for everyone for proper eye relief.
Tim