erickrschaefer: You certainly practice well and your ethics on taking shots are pretty high. I've watched prized bucks just meander around and out of shot distance, not wanting to miss on a long shot but your practicing techniques sound pretty effective.
I have used clay pigeons - the ones the trap and skeet shooters managed to miss (LOL) and I have also used small ballons out to distances of 50 yds. Even though I consider myself a good hunting handgun shot I still won't take shots beyond what I consider to be my effective range. I always felt that was a hunter's responsibility but never really had and sort of confirmation on that until I came to this site and began to realize that there are a ton of dang good handgun hunters around who have the same ethics. And I am dang pround to be here.
I would say there is nothing wrong with your practice techniques or your hunting ethics. But, you didn't identify what you were hunting with and whether that is capable of a 100 - 125 yd shot. If your hunting handgun is capable of that range and you practice out to that range as effectively as you do now, that buck will be on your dinner plate next time around.
I would say practice some more and practice for that long shot, but only if you feel both your caliber and you are capable of making it. Mikey.