I have not shot the Barnes bullets in my 480 yet. H-110 should be the powder to use. My main bullet is a 370 grain cast with 25 grains of H-110. Ihave shot hogs so far but no deer. I have shot the 325 XTPs and they shoot great in my Raging Bull. If your shots are within 35 yards, I would start with the max 325 grain load with the Barnes bullet and work up a little if needed. With 35 yard deer, you should be happy with the 325 grain loading and the Barnes bullet. I think Barnes has loading data in their newest book for the 480.
Good shooting,
Dave
Sharps made the west safe for Winchester!