kb,
I must agree with Graybeard and Lloyd. Many years ago I used the Hornady 240 XTP exclusively in my Ruger SRH. I did expansion tests in Computer Shopper Magazines (that was about all I thought they were good for and each issue was 1.5" thick at that time!!!) and expansion was picture perfect. I know that magazines don't necessarily indicate deer, but it gave a media to compare various slugs. I did shot only 2 deer with the SRH and 240 XTP bullets, and death was abrupt. Distances were both less than 50 yards and the deer where hit in the shoulder area--heart/lungs.
Now to Lloyd...I have since become a cast bullet man!!! I now mostly only shoot cast in the 44's. Accuracy is good for the 429650, 44-240-SWC, and the 44-250-K bullets. I may never go back to jacketed bullets in most calibers that I presently shoot!!!
So, if you don't cast your own slugs...The XTP would be my choice. Good-luck...BCB