i like the .256, got a couple of them in fact, but it is at times a very irritating cartridge to deal with. Very finicky.
4064 is a bit too slow, never had any luck with the slower powders, at least in the 3 i've owned so far.
Stick with H110, AA1680, LilGun, 4198, 4227, etc. For most shooting i use the 75 grain Hornady, but i have a special Virgin Valley quick twist .256 that is my .25 "Whisper", where i use reformed .221 Fireball brass & replaced the extractor to a rimless one for a .223. It has a long chamber throat so i can seat 117/'s / 120's way out & get more case capacity so its probably not a fair comparison to include it as a regular .256 mag.
My regular one is a 12" tube, also by Virgin Valley, what it likes it shoots fairly well & what it doesnt like it slings so bad i have to work to keep them on paper. I havent had a lot of luck with finding Max loads it shoots well, but does tolerably well with loads that are about 85 - 90% of maximum. It also does fairly well with the 86 grain el-cheapo Rem SP's that are used in the .25/20. If you do prefer heavier bullets, slightly slower powders with burn rates up to H322/Reloader7 , etc will work fairly well with full powered loads. So far i have not found any cast bullet loads it likes, but am still trying.
Hope this helps.