Don't use the 45g Sierra spitzers on game!!!
That bullet at Hornet velocities acts just like a FMJ. It's an extremely tough bullet. I shot quite a few groundhogs with it, a few coons, and a couple foxes before I completely gave up on it for the Hornet, or 218 Bee.
A very good bullet in the Hornet besides what the others posted here is the 50g Sierra semi points. It hits hard, and is usually accurate in most rifles.