sawfish is correct..the 350's will NOT expand readily on deer very well, which is why i chose them for last weeks hunt on bigger stuff...i put a couple of pix on the TC handgun forum of some of the results just today. Using the 350 grain Hornady one shot went through both front shoulders of a Buffalo & lodged under the hide on the other side, i still have it. havent weighed that bullet yet, i though i will tonite when i get home, i am curious as to how much weight it retained. It did expand but that may not be a valid comparison since it hit plenty of big heavy bones.
The shot that took the Bull Elk didnt stop at all, it punched through the ribcage on the onside, and broke the offside shoulder on the way out the other side, i didnt get that bullet back.
i have take several deer & 2 hogs with the 300 grain loads & they open up nicely, even at slower speeds, i get the impression the Remington 300JHP is the softer of the 2....
sawfish; i havent tried the CPBC 405's...they shoot fairly well in your guns?
i shoot the 45/70 is an SSK 14" TC, a 21" TC Carbine, and a Ruger #1...its a fine caliber...