I have used varget for a few chamberings, its good, but not the best. It is versitile in that is is rarely a poor choice. Kind of a jack of all trades powder. It meters well.
I find it better for the lighter for chambering bullets, I still use it for my 125/130 target rounds in the -06, it can handle 150s, but not to my satisfaction for hunting deer.
I use it in the 243 also because I am only pushing 75 or 80 gr target punchers. Same for the 270 wsm, only the varmint weight bullets.
One other thing, Hodgdon has a lot of data for using this powder, so if you want to minimize the amount of powder kegs you have on the shelf, and are not looking for the absolute fastest or the absolute most accurate performance, it is a great choice. To achieve the fastest and most accurate, you will have to experiment with many powders.