well you know my choice is the 265...a bit less recoil, flatter trajectory, & good penetration..if you were chasing stuff bigger than deer i'd go the 300 route...
Just for giggles what did Sierra recommed for a load on that 300 ? I couldnt get that thing to expand even out of my 445 Supermag 20" carbine, that thing is tough, and i bet it would shoot one stem to stern!