Is the front sight retained by a plunger near the muzzle like the Redhawk/GP-100? If so, you're in business, if not it would likely be a custom proposition.
I've had the Gold Bead/V notch rear sights on both my Redhawks, and I'm convinced there is no better sight system for me. Your mileage may vary, but Ruger has sold an awful lot of them!
PJ