Knight will also tell you that powerbelt bullets are terrible, but many people still love them. 45's are no diiferent than 50's, they just need some load development, and no two are the same. The most accurate MZ that I own is a .45 and I own 10 MZ's. It's true that .50 cal is the most popular, legal in the West, easiest to find bullets for. However the .45 does hold an advantage over the .50 in terms of trajectory. Even if both guns shoot the same weight bullets, the .45 will generally shoot better because the bullet is longer and will stabilize better. If all that your ever going to kill is a deer and the .45 is on sell, buy it. If your going to kill anything bigger, buy a .50. Just make sure you buy a good gun, because a bad gun won't shoot anything good.