Well, it's all about opinions. We have a steel target at 200yds. at our range here that I have no problems hitting with the 500.
When at the range the other day, there was a guy who said a friend of his shot an elk with a 50 BMG. He said it took him hours to find it. So the questions is, how far do you want to shoot with a handgun?
A bear I shot last year with my .500, I spotted probably a mile away. I stalked him to within about 30 yards. It was very exciting as my son and I came over the last little rise, not knowing where the bear would be since we hadn't been able to see him for a while. And then for him to be that close was awesome. Using a 50 BMG, I could have shot him from where I spotted him, but how much would that have been? The challenge of using a pistol is to get closer, not to shot a rifle bullet out of a pistol in my opinion.
By the way, my three of a kind .500's,460 high, I believe beats your two pairs. Just kidding with you.