I would like to hear what all of your sighting in practices are. I am familiar with ballistics and maximum point blank range, but it seems that all the old timers around here don't put a whole lot of stock into that. In fact, I would bet that most of them (who always get their deer) are sighted in at 100 yards, give or take a few. Their reasoning seems to be that distance is more than adequate for most hunting and its nice to keep your bullet close to the line of sight for those sometimes neck or head shots up close.
Personally, I sight in my iron sighted rifles at 100 yards, theory being that I can't see well enough to shoot much past about 150 yards, and my scope sighted rifles are sighted dead on at 200. I like having a target with holes in it at the exact point I am aiming, it gives me more confidence, and I can't see myself ever shooting past 300 yards anyway.
Of course, I have places where I can shoot that far and farther, and I am sure that factors in a bit also.