Last deer season, used a 243 Winchster Ballistic silvertip 95 grain on a doe. Hit her just behind the shoulder. Bullet passed thru the deer (part of the lung was hanging out the exit wound). This deer was shot at about 25 yards, and she ran off about 100yards before dropping. I had a very good blood trail to follow, so I can not complain. FYI, I switched to a 308 after that day.