I spawned a thought just now (I know...doesn't happen often).
For my 300 Weatherby, my go to load has been a 180 grain Nosler Partition over IMR7828 SSC.
Nosler manual[/u]
80.5 - 84.5 grains of IMR7828
IMR manual(same bullet)[/u]
72.5 - 80.3 grains of IMR7828
I don't know about you, but I think that's QUITE a span. And the fact that the Nosler MINIMUM is the IMR MAXIMUM??? A little scary, I think. Also, the Speer manual is pretty close to the Nosler data. I have sent an email to the Nosler Forum administrator and await his response.
Whaddaya think?