while i would definitely restrain a rifle that is in a canoe, so as not to lose it if tipped over, {yeah, Mac's right!} i still think that the rifle is the better choice for protecting, hunting, and helping with a lady aiming/handling the thing. sure, women can handle handguns; but .357 rifles are easier on the shooter than even a heavy Ruger double action revolver. the recoil and the muzzle blast are Both part of the equation. i myself have used both the Marlin in .357 and the Ruger GP-100.......so i know.
i'd get a .44 mag' any day ahead of a .357 or .41 mag, or a .45 LC, for hunting, and protection. it's just more versatile with light loads for small stuff and thumpers for 'whatever'. but, can momma handle one?
a .357 with 180 or 200 grain bullets of proper construction can readily hunt and provide protection to maybe 150 yards.
but, those are just my opinions.
good luck,
ss'