The process of soaking the skull in water is called Maceration. It's actually the action of bacteria, primary e-colli which eats away at the meat. It can stink to high heaven, and it's a good idea to change the water when it gets putrid smelling. The bacteria, being live organisms will excrete waste, eventually turning the water so toxic, that not even themselves survive. After all of the flesh "disolves" away, you may safely dump it into your sewage system. Run a garden hose into your container and let it overflow until your water is running clean, obviously best done outside. Now you can go ahead and make a soaking solution of water and a little nice smelling liquid dish detergent, Dawn is very good as it has extra grease cutting capabilities. After a couple of days, your skull can be pulled out and set in the sun to dry and whiten. If you want an extra bright white skull, wrap your skull with an old towel, cotton batting from wally world works well too. Soak down the cloth with hydrogen peroxide, taking care not to put the peroxide on the antler burrs. A little masking tape, combined with the toweling will usually keep the peroxide on the skull where it belongs. Cover the soaked cloth with plastic wrap, or put it into a plastic bag, and set it aside for a couple days. After that, remove the plastic and soaked cloth, and set your skull in the sun. Peroxide is much more gentle on the bone than clorine bleach, and will result in a noticeably brighter finished skull, than when it's not used. After drying for a week or so, you can use elmers glue to glue in any loose teeth. The best material I've found for coating and protecting whitened skulls is Krylon Triple Thick Acrylic close. Best applied in a couple light flash coats, then one thicker wet coat. Of course if you prefer a matte finish, Krylon has some great matte sprays as well. Many professional skull cleaning will use a wax based finish, but the krylon is much more user friendly. Try and use plastic gloves when handling the skull during the maceration process, as a very high concentration of e-colli bacteria can be dangerous. At very least, be sure and wash your hands in an anti-bacterial soap immediately after handling.