In order to get a safe load with the fairly fast burning H-4198, you'll
probably need somebody around here to run the variables in one
of those loading programs.
Just looking in a few manuals and online, I got close with data
for a 140 grain cast bullet, and IMR-4198. In the interests of safety
though, I hesitate to toss that load data out as a possible solution.
Assuming a worst case scenario ( like nobody comes up with a load ),
I'd say just be careful as to bullet placement.
I took out an 8 pointer with the same Nosler bullet in a .260 at
no more than 30 yards a couple of years ago. At that range,
making a neck shot was no problem. A broadside lung shot should
also work, even with the closer ranges. Just try to avoid any shots
at shallow angles, where the bullet's speed and construction might
result in less than adequate penetration.