I did this alot in 45-70 with great results. HOWEVER, I tried it recently in a 50-70 Contender with a 6-1/2" barrel, and got some very spooky/weird results. as in 2 or 3 booms/normal muzzle flash to basically a stun grenade in your face and a bullet in the dirt 30 feet out. I went and read a little more on the filler subject, and now I will be a little more cautious as to their use. Like I said, they work great in some applications, and not so in others, Figuring out which it will be is the hard part. If in doubt, find someone that has done it consistantly for years to get your info from, not someone who fired 10 rounds without a problem. By the way I will now be taking my own advice. As a side note I just had a good conversation with a tech at Hodgden, about their new Trailboss powder in large cases. I haven't tried it yet, (my order hasn't come in yet), but it sounds great for filling up large cases in light loads. It is fast and clean burning, and so fluffy that a 1 pound can only holds 9 ounces! I'll let you know how it works.