Yep! there are those who swear by loading "X" amount away from the rifling while others swear over the process until they find their rifle's "sweet spot". Like Questor I use the specs supplied in the data for seated length. That way the load is predictable and should be safe to load in any rifle in good condition. I did once try to seat a bullet, a 180 gr BTSP, out close to the rifling in my 03A3 30-06. I was beginning a workup of a new load so I used the minimum listed load of WW760 powder, the large rifle primer listed, a WLR primer, and because I had such a long free bore I allowed the bullet to find its depth by closing the bolt on the cartridge with the bullet barely seated in the case. This seating depth was less than 1/2 of one caliber deep. When I fired the first of three rounds, it sounded "funny" like a cap and ball rifle more than a modern cartridge gun. The second shot sounded like a flint-lock with a pufft followed almost immediately by a boom. If I ever get that kind of sound again I will stop and pull the remainder of the bullets apart to check all the components. The third round fired as a pop - from the primer and silence for about a full second and then the loudest boom I have ever heard from any rifle and a recoil that hurt like nothing I had felt from my '06 before. I knew that was so wrong on so many levels I just sat there stunned for a long time. I looked the gun over and it seemed fine and I had no cuts or scratches - other than the bruise to my shoulder I was fine. I opened the bolt - harder to do than ever before. I pulled what used to be a 3006 cartridge out of the bolt. The rim - yep! it now had a rim was over 9/16 inch in diameter, the primer pocket was so large that the primer had fallen out as I removed the case from the gun and it was badly deformed. The head of the case was over-expanded and bulged to a point just in front of the web where there was a split that was open and about a third of the way around the case.
I inspected the gun and it seemed to be in good shape but I packed everything up and took it all to the gunsmith.
He checked my gun over with gauges and micrometers and announced that it was in great condition. I asked him what happened - after telling him about my experience. He explained that I had experienced a situation that "can't happen". When I used the minimum load and combined that with the long seating of the bullet it reacted like a very light load of slow burning powder in a large case. The primer had gone off separating the bullet from the case and lodging it in the rifling while blowing the powder all over inside of the case without properly igniting it. He said that there were probably a few grains of powder burning in several different locations in the case and they gradually burned, igniting more of the powder as they burned. At some point the heat was high enough to pruduce an increase in burn rate as the pressure began to rise. The powder began to burn very fast - from several different places in the chamber and the pressure wave and burn rate all came together at once, known as detonation, which caused the pressure to go well beyond anything similar to normal pressure. Looking at the case he said the pressure was probably close to 100,000 psi and told me I was very lucky to be uninjured and it was a miracle that my gun was in shootable condition.
Since that experience I use the listed load data as listed. Period! I start new loads with minimum powder charges and bullets seated to the listed O/all length. I work my loads up in increments and when I find an accurate load that is close enough to maximum to know there won't be another accurate load closer to but not exceding the maximum listed load.
When I find my accurate load I load more of it and some on either side of the load in .2 (2/10 ) of a grain increments. I use this data to find the limits of the loads accuracy envelope. I can play with primers to see if they affect the accuracy. The most stable primer - the one that provides the widest range of accuracy is the one I choose. I then pick the accuracy load that is close to the center of these accurate loads. The most accurate load (usually) allows for the greatest range of error that will not affect the point of impact of these bullets. I then load a box or two of this load. I fire it over a period of several weeks using a "first shot" target and a "cumulative aggregate" target system where I place a target on the board with another one over it. I fire five shot groups and replace the overlay target with a new one. I five five more shots. I continue this until I have fired no less than three separate times at the range and collected at least one three shot aggregate on the first shot target and three 20 round aggregate targets and their five shot individual targets. I compare the first shot point of impact with the aggregate and individual group target points of impact to determin whether the first shot from a cool dry barrel hits outside the "average point of impact" or that changes occur in the groups under the differences in conditions over the four or five week period of time that I have been firing. I measure all of the five shot groups for an average group size and compare this size to the aggregate group size and compare the group of first shots with the group size for the single five shot groups and the aggregates to make sure that my average group size represents a true representation of the accuracy of the load and rifle. I record all data at each session and at the final evaluation session.
I test the load over the chronograph with a minimum of 40 rounds to get a good sample of the velocity, mean average deviation, standard deviation, extreme spread and the high and low velocity produced. Then I calculate the trajectory and site in range (point blank range) for a target size of 2" diameter. After this I run tests through my fackler boxand at ranges to test the trajectory print outs. Clicks above to extend point blank hold to ranges beyond my PBR are calculated out to a maximum hunting distance. (my personal limit is 200 yards)
This is how I spend my time working up a new load for my rifles and pistols. Once a bullet is tested in the fackler box I dont have to test it again unless it's construction is changed. I can calculate the reaction up or down for velocity using the expansion index calculation in my software and compare it to other bullets that I have tested.