I have killed a few deer with the 55 grain soft point load and several deer with a 45 grain hollowpoint out of a 223. The bullets performed relatively well for what I was using them for. But keep in mind, I was not "hunting" with these bullets but rather "shooting", I was taking deer for either biological study or dispatching wounded deer. I would always use neck or head shots and was usually shooting 100 lb or so does. I went to the 45 grain bullet because occasionally a 55 grain bullet would exit and since I was usually in a populated area, this wasn't good. I never had a 45 grain exit on a head or neck shot. The deer dropped where they stood. I have seen deer shot with a 223 in the body cavity and while they expired quickly and really didn't travel very far, there was little to no blood trail so in a thick area locating the animal could be difficult. But for hunting, I wouldn't be comfortable using these bullets unless the person is calm enough to wait for the perfect shot and mature enough to let animals walk if the perfect shot isn't there and is using a rifle capable of very percise accuracy and the shooter is capable of utilizing the rifles potential. I guess what I am saying is the 223 will kill deer cleanly but there is absolutely no margin of error on shot selection, shot location, and shot placement.