Whitetails are rather easy to kill with a properly placed shot. My recommendation would be to use a 240gr jacketed hollowpoint on them for the quickest kill. I have shot whitetails with hardcast 44mag bullets and they do not take them down nearly as fast. Not in my experience anyway.
As to the hogs, it really depends on how big they are. Average size hogs seem to get killed by everything, if you read the boards enough. I shot an average boar (estimated at 200lbs) with a 44mag - 265gr soft point bullet and it went right through. There is much discussion that large boar take a lot of killing. Here is what I observed a few weks ago when my buddies and I shot 3 boar that all weighed over 300lbs.
454 Casull w/ 300gr Swift A-Frame - bullet passed right through
44 mag w/250gr Nosler Partition - bullet passed right through
44mag w/300gr Hard Cast bullet - bullet passed right through
50cal muzzleloader w/295gr Powerbelt Slug & 150gr Cleanshot
- bullet passed right through
All the boar had short lifespans, the 454 Casull put the boar down the fastest and left an unbelievable 2.5' wide blood trail for 40 yards.
Yea, we had a lot of fun on that hunt. VH