Mike,
I don't have direct experience with the .450 Marlin, but I am shooting that bullet out of my .458 Win. I can tell you that it is a very long bullet, and therefore eats up quite a bit of case capacity. You should be able to seat it out some in your Encore, which will help, but keep in mind that Barnes recommends their bullets be seated about .050" off the lands.
You didn't say which powder you are using, or want to use. I checked my Barnes manual, and as you stated, the data does not show loads for their longer spitzer bullets. A little extrapolating leads me to believe that you could use their starting loads for the 400 grn. bullet with the 450 grn. TSX.
I started with IMR 3031, but switched to H4895. It is a bit more energetic, giving me better velocity, and is a smaller grained powder, which has helped with loading density. The Barnes manual shows a minimum charge of 48.5 grns. with the 400 grn. bullet, and a maximum of 52.5. If you load to a case capacity that is only lightly compressed, I believe you will be fine. If the starting load mentioned seems to be compressed too much, reduce it by 10%.
I'm not certain that the Marlin round will drive this bullet with sufficient velocity to make it perform, but it sounds like it would be worth a try. They are pricey at $1.00 each, and those all copper bullets really do foul up a barrel. Best of luck with your loading project. Let us know if they shoot well for you!