I have found it interesting how the cartridge makers were lazy. They came up with one rim size and made a dozen cartridges with different names (and very little other differences) by making the body of the case longer or shorter. .45/70 was a government cartridge and from there... .45/120 WCF (.45 Sharps' 3 inch straight? same cartridge) was the hot rod. 300 grain bullet at around 1800 fps. .45/60 WCF was the whimp for the less strong 1876 Winchester lever actions. More "thump" meant bigger diameter. 500 grain bullet, but now 50 caliber... These were black powder rules and pressure was not controllable much above 20K CUP. Ladies guns were like the .32/40 afield and for the garden/back yard .25/20 WCF or single shot... The first .22 rimfire was for shooting indoors into the fire place. (BB Caps, then CB caps). .22 Hornet with black powder was the .22 WCF.
I built a .45/70 on a Siam Mauser for the strength of action, then learned about the brass. Ahhh experience.
.45/70 Government case was necked to .375 to make the .38/56 (not .38/55 which is on the .30/30 case/rim). Or the .40/65. 50/110 case survives as the rim/parent of the .348 Winchester. Little short--.348 case, but probably do .50/70 gov alright. .405 WCF was based on the .30/40 Krag/.303 British rim and worked at the new, higher smokeless pressure, post buffalo era, circa 40K CUP like the .30/30 WCF (which is the .32/40 case necked down and blown out for 1894! Not to forget the .32 Special, same case. .321 bullet, blown out...)
So when you do your homework, Cartridges of the World for instance, you will find the "round" that "calls" to you and then it is how much gun you wish to tote. Big rounds mean big machinery MEANS heavy. The old hi walls had the right amount of modern steel for 1885. Today you can put the .243 in a low wall, or at least Browning catalogues it... Oh yes, the lighter guns kick more. What is your pleasure? How much abuse...? I can understand the long barrels and crossed sticks of the buffalo hunters. More weight, less sharp recoil. Big bullet = big hole in buffalo lungs = dead buffalo. So how is your heart? Or do you have a pick up to haul this piece of artillery? (ha, ha) ENJOY luck.